Dolutegravir Impurity 42 CAS CATO-C4X-162042
| CAS No. | CATO-C4X-162042 |
| Molecular Formula | C21H21F2N3O5 |
| Molecular Weight | 433.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dolutegravir Impurity 42 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dolutegravir Impurity 42 (CAS CATO-C4X-162042), molecular formula C21H21F2N3O5 and molecular weight 433.41 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Dolutegravir Impurity 42 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 433.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Dolutegravir Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H21F2N3O5 |
| Molecular Weight | 433.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dolutegravir Standards
- Dolutegravir Impurity 15 (CAS 2384108-28-3)
- Dolutegravir Impurity 34 (CAS 2227442-13-7)
- Dolutegravir Impurity 35 (CAS 2583719-57-5)
- Dolutegravir Impurity 58 (CAS 2244245-35-8)
- Dolutegravir Impurity 69 (CAS CATO-C4X-162069)
- Dolutegravir O-Methyl Impurity (CAS 1335210-35-9)
- Dolutegravir Impurity 62 (CAS CATO-C4X-162062)
- Dolutegravir M3 (CAS 1485692-24-7)
Recommended Standards
- Cabotegravir Impurity 14 (CAS CATO-C4X-287614)
- Nimodipine Impurity 36 (CAS CATO-C4X-138536)
- Cabotegravir Impurity 15 (CAS CATO-C4X-287615)
- CAS 2140807-17-4 (CAS 2140807-17-4)
- 2-(2-aminophenoxy)-N-(pyridin-3-yl)acetamide (CAS 926205-74-5)
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- 1,3-Bis(4-fluorophenyl)-4,7-diphenyl-4,7-dihydroisobenzofuran (CAS 132980-69-9)
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- Methyl 2,4-dioxo-4-(4-propoxyphenyl)butanoate (CAS 889996-17-2)
- 3-Isopropoxybenzenesulfonyl chloride (CAS 69129-61-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com