Entacapone impurity 42 CAS CATO-C4X-162942
| CAS No. | CATO-C4X-162942 |
| Molecular Formula | C8H9Cl2N3O2 |
| Molecular Weight | 250.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Entacapone impurity 42 (CAS CATO-C4X-162942), a pharmacopoeial impurity reference standard (molecular formula C8H9Cl2N3O2, MW 250.08 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Entacapone impurity 42 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 250.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Entacapone impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2N3O2 |
| Molecular Weight | 250.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Entacapone Standards
- Entacapone EP Impurity F (CAS 160391-70-8)
- Entacapone Impurity 59 (CAS CATO-C4X-162959)
- Entacapone Impurity 6 (CAS 158693-01-7)
- Entacapone Impurity 1 (CAS CATO-C4X-16291)
- Entacapone EP Impurity G (CAS 1364322-41-7)
- Entacapone impurity 18 (CAS CATO-C4X-162918)
- Entacapone impurity 53 (CAS CATO-C4X-162953)
- Entacapone impurity 52 (CAS CATO-C4X-162952)
Recommended Standards
- Mosapride impurity 44 (CAS CATO-C4X-104459)
- Opicapone Impurity 76 (CAS CATO-C4X-240476)
- 1-AMINO-2-IODO-4-CYANOBENZENE 33348-34-4 4-AMINO-3-IODOBENZENECARBONITRILE 4-AMINO-3-IODOBENZONITRILE 4-CYANO-2-IODOANILINE 4-amino-2-iodobenzonitrile TF10227 (CAS 33348-34-4)
- 4-(3-Bromophenoxy)pyridine (CAS 1016494-33-9)
- Opicapone impurity 26 (CAS CATO-C4X-240426)
- Chlorpromazine EP Impurity D (CAS 1225-64-5)
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- 2-(4-Methylphenyl)butanedioic acid (CAS 66483-40-7)
- Nicorandil Impurity 34 (CAS CATO-C4X-190734)
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- 3-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1190321-60-8)
- Cyclolinopeptide B (CAS 193139-41-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com