Entacapone EP Impurity G CAS 1364322-41-7
| CAS No. | 1364322-41-7 |
| Molecular Formula | C11H9N3O5 |
| Molecular Weight | 263.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Entacapone EP Impurity G (CAS 1364322-41-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H9N3O5 and a molecular weight of 263.21 g/mol.
Entacapone EP Impurity G (C11H9N3O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9N3O5 |
| Molecular Weight | 263.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Entacapone Standards
- Entacapone impurity 18 (CAS CATO-C4X-162918)
- Entacapone Impurity 1 (CAS CATO-C4X-16291)
- Entacapone impurity 52 (CAS CATO-C4X-162952)
- Entacapone Impurity 72 (CAS 893419-47-1)
- Entacapone EP Impurity F (CAS 160391-70-8)
- Entacapone Impurity 59 (CAS CATO-C4X-162959)
- Entacapone impurity 42 (CAS CATO-C4X-162942)
- Entacapone Impurity 2 (CAS 150995-46-3)
Recommended Standards
- Lansoprazole Impurity 14 (CAS 112525-75-4)
- Roflumilast Impurity 58 (CAS CATO-C4X-193558)
- 1,10-Phenanthroline,4,7-dichloro 4,7-dichloro-1,10-phenanthroline 5394-23-0 NSC626 (CAS 5394-23-0)
- Opicapone impurity 17 (CAS CATO-C4X-240417)
- Baloxavir Marboxil Impurity 227 (CAS CATO-C4X-2108227)
- Lisinopril EP Impurity H (CAS 138247-43-5)
- Diazoxide impurity 11 (CAS CATO-C4X-195211)
- 5-Fluorobenzo[d]isoxazol-3-amine hydrochloride (CAS 916571-99-8)
- 1-(4-methoxycyclohexyl)propan-1-one (CAS 859055-52-0)
- 1,4-Ditosylpiperazine (CAS 17046-84-3)
- 2',7'-Dibromospiro[cyclopentane-1,9'-fluorene] (CAS 441771-49-9)
- 2-Chloro-4-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 1603054-40-5)
- 1-Methyl-3-(thiophen-2-yl)-5-(trifluoromethyl)-1H-pyrazole (CAS 650615-64-8)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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