Fluticasone Impurity 108 CAS CATO-C4X-1650108
| CAS No. | CATO-C4X-1650108 |
| Molecular Formula | C26H31FO8 |
| Molecular Weight | 490.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, Fluticasone Impurity 108 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 490.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Fluticasone Impurity 108 (CAS CATO-C4X-1650108) is a certified pharmaceutical impurity reference standard with the molecular formula C26H31FO8 and a molecular weight of 490.52 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H31FO8 |
| Molecular Weight | 490.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Furoate EP Impurity A (CAS 397864-63-0)
- Fluticasone Furoate EP Impurity B (CAS 80474-24-4)
- Fluticasone Impurity 50 (CAS CATO-C4X-165050)
- Fluticasone Impurity 39 (CAS CATO-C4X-165039)
- Fluticasone Propionate Dithioacid (CAS CATO-C4X-165047)
- Fluticasone Propionate EP Impurity B (CAS 948566-12-9)
- Fluticasone Propionate Fluoromethyl Ester Analog (CAS 1174034-79-7)
- Fluticasone Impurity 42 (CAS CATO-C4X-165042)
Recommended Standards
- 5-(4-Butoxyphenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-63-8)
- Relugolix Impurity 184 (CAS CATO-C4X-2429184)
- Proxyphylline Impurity 2 (CAS CATO-C4X-24402)
- ((2,4,4-Trimethylpentyl)phosphoryl)bis((2,6-dimethoxyphenyl)methanone) (CAS 145052-34-2)
- Cycloserine Impurity 15 (CAS CATO-C4X-226415)
- Celiprolol Impurity 9 (CAS CATO-C4X-24549)
- Baclofen Impurity N3 (CAS 69856-22-0)
- Naphthofluorescein di-O-(b-D-galactopyranoside) (CAS 133551-98-1)
- N-(3,4-Dimethylphenyl)-2-((4-phenyl-1H-imidazol-2-yl)thio)propanamide (CAS 332101-64-1)
- 4-(4-(2-Morpholinoethyl)piperazin-1-yl)aniline (CAS 1018250-14-0)
- Letermovir impurity 56 (CAS CATO-C4X-291556)
- 1-(4-Methoxypyridin-2-yl)ethan-1-one (CAS 59576-28-2)
- [(2H-1,3-benzodioxol-5-yl)methyl](propan-2-yl)amine (CAS 68291-92-9)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
Why CATO?
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