Iohexol EP Impurity F HCl (4,6-diiodo Isomer) CAS CATO-C4X-166423
| CAS No. | CATO-C4X-166423 |
| Molecular Formula | C14H19I2N3O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Iohexol EP Impurity F HCl (4,6-diiodo Isomer) (CAS CATO-C4X-166423, C14H19I2N3O6HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Iohexol EP Impurity F HCl (4,6-diiodo Isomer) (C14H19I2N3O6HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Iohexol EP Impurity F HCl (4,6-diiodo Isomer) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H19I2N3O6 HCl |
| Molecular Weight | 615.58 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Iohexol Standards
- Iohexol Impurity 31 (CAS 1096689-22-3)
- Iohexol EP Impurity F (CAS 1215856-35-1)
- Iohexol Impurity N9 (CAS 122731-58-2)
- Iohexol Impurity 13 (CAS 122731-74-2)
- Iohexol EP Impurity D (CAS 157739-09-8)
- Iohexol Impurity 51 (CAS 1651211-78-7)
- Iohexol EP Impurity H (4,6-diiodo Isomer) (Mixture of Diastereomers) (CAS 1651211-79-8)
- Iohexol EP Impurity I (CAS 196309-19-0)
Recommended Standards
- Desloratadine Impurity 9 (CAS 117796-52-8)
- Pranoprofen Impurity 65 (CAS CATO-C4X-181165)
- Dotinurad Impurity 90 (CAS CATO-C4X-249490)
- 2-(4-Ethylpiperazin-1-ylmethyl)benzoic acid (CAS 914349-54-5)
- 2-(4-Methoxyphenyl)-2-phenylacetaldehyde (CAS 16343-36-5)
- 2-Methyl-1,1-dioxo-1-benzothiophen-3-amine (CAS 1423026-07-6)
- (E)-4-(4-acetylphenylamino)-4-oxobut-2-enoic acid 24870-12-0 4-(4-Acetylanilino)-4-oxo-2-butenoic acid (CAS 24870-12-0)
- Potassium (2,6-dimethylphenyl)trifluoroborate (CAS 561328-67-4)
- 5-Bromo-3-methyl-2-(propan-2-yloxy)benzaldehyde (CAS 1564722-77-5)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com