Lisinopril Impurity 13 CAS CATO-C4X-168113
| CAS No. | CATO-C4X-168113 |
| Molecular Formula | C20H25F3N2O6 |
| Molecular Weight | 446.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lisinopril Impurity 13 (CAS CATO-C4X-168113) is a certified pharmaceutical impurity reference standard with the molecular formula C20H25F3N2O6 and a molecular weight of 446.42 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Lisinopril Impurity 13 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H25F3N2O6 |
| Molecular Weight | 446.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Lisinopril Standards
- Lisinopril Impurity 14 (CAS CATO-C4X-168114)
- Lisinopril Impurity 16 (CAS CATO-C4X-168116)
- Lisinopril Impurity 15 (CAS 116169-90-5)
- Lisinopril EP Impurity F (CAS 1132650-67-9)
- Lisinopril-D5 (CAS 1356905-39-9)
- Lisinopril (CAS 76547-98-3)
- Lisinopril EP Impurity E (CAS 85955-59-5)
- Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers) (CAS 1092813-99-4)
Recommended Standards
- 2-((2,6-Dichlorobenzyl)thio)-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 354556-54-0)
- (3-(1-Benzyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-1-yl)(2-(trifluoromethyl)phenyl)methanone (CAS 477711-19-6)
- 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione (CAS 752222-83-6)
- 4-Phenyl-3-(1-{2-[4-(trifluoromethoxy)phenyl]acetyl}piperidin-4-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775532-47-2)
- CAS CATO-C3D-262789 (CAS CATO-C3D-262789)
- Flurbiprofen Impurity 111 (CAS CATO-C4X-1444111)
- Alprazolam EP Impurity B (CAS CATO-C4X-146014)
- thieno[3,2-b]pyridin-6-ylmethanamine (CAS 1306604-20-5)
- 6-Chloro-N-(2-cyanoethyl)-N-phenylnicotinamide (CAS 1019354-92-7)
- Rimegepant Impurity 142 (CAS CATO-C4X-2487142)
- [[4-Benzyloxy-3-methoxyphenyl]methyl]butanedioic Acid Ethyl Ester (CAS 1391054-03-7)
- N-(3-Butyl-2,4-dioxo-1,2,3,4-tetrahydrobenzo[g]pteridin-8-yl)acetamide (CAS 374615-45-9)
- Methyl 4-Cyanocinnamate (CAS 52116-83-3)
- Peptide T (CAS 106362-32-7)
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