LCZ-696 Impurity 53 CAS CATO-C4X-169653
| CAS No. | CATO-C4X-169653 |
| Molecular Formula | C20H23NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, LCZ-696 Impurity 53 (CAS CATO-C4X-169653, C20H23NO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H23NO2HCl, LCZ-696 Impurity 53 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 345.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures LCZ-696 Impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23NO2 HCl |
| Molecular Weight | 345.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Pentazocine Impurity 4 (CAS CATO-C4X-31644)
- Tranexamic Impurity 26 (CAS CATO-C4X-177126)
- Buspirone EP Impurity C (CAS 257877-45-5)
- 3-[(4-ethylphenyl)amino]-1,1,1-trifluoropropan-2-ol (CAS 1343644-03-0)
- 2-(2-Fluoro-5-methylphenyl)propan-2-ol (CAS 1343867-43-5)
- 4-((2,2-Dimethoxyethyl)amino)-2H-chromen-2-one (CAS 156742-55-1)
- methyl 6-chloropyridazine-3-carboxylate (CAS 65202-50-8)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole hydrochloride (CAS 2377608-65-4)
- 3-(Cyclohexyloxy)propan-1-amine (CAS 16728-63-5)
- Gastrin Tetrapeptide (CAS 1947-37-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com