Buspirone EP Impurity C CAS 257877-45-5
| CAS No. | 257877-45-5 |
| Molecular Formula | C20H30N8 |
| Molecular Weight | 382.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Buspirone EP Impurity C is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Buspirone EP Impurity C (CAS 257877-45-5), a pharmacopoeial impurity reference standard (molecular formula C20H30N8, MW 382.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Buspirone EP Impurity C (C20H30N8) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 382.51 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H30N8 |
| Molecular Weight | 382.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 8 |
Related Buspirone Standards
- Buspirone (CAS 36505-84-7)
- Buspirone EP Impurity N (CAS 257877-44-4)
- Buspirone-d8 Hydrochloride (CAS 204395-49-3)
- Buspirone impurity 01 (CAS 105496-33-1)
- Buspirone N-Oxide (CAS 220747-81-9)
- Buspirone impurity 38 (CAS CATO-C4X-125838)
- Buspirone EP Impurity E (CAS 257877-43-3)
- Buspirone impurity 28 (CAS CATO-C4X-125828)
Recommended Standards
- Perfluoroheptanoyl Chloride (CAS 52447-22-0)
- Flurbiprofen Impurity 20 (CAS CATO-C4X-144420)
- 7-Chloro-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptanoyl fluoride (CAS 662-63-5)
- Flurbiprofen Impurity 22(Mixture of Diastereomers) (CAS CATO-C4X-144422)
- Carbocisteine Impurity 49 (CAS 907565-13-3)
- Dexamethasone Impurity 129 (CAS CATO-C4X-1165129)
- Hydroxyzine Impurity 5 (CAS 2469273-48-9)
- Ertugliflozin impurity 57 (CAS CATO-C4X-301157)
- (R)-4-(tert-pentyl)-2-(pyrrolidin-2-yl)phenol (CAS 1213956-70-7)
- tert-Butyl 4-(3-m-tolylureido)piperidine-1-carboxylate (CAS 1233953-12-2)
- Methyl 4-iodo-1h-indazole-3-carboxylate (CAS 1360964-29-9)
- 5-Bromo-2-methyl-6-(4-methylpiperidin-1-yl)nicotinic acid (CAS 1443290-37-6)
- Ethyl 2-(4-(2,6-difluorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate (CAS 861206-30-6)
- Semaglutide impurity 50 (CAS 2773558-66-8)
Why CATO?
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