Paliperidone Impurity 108 HCl CAS CATO-C4X-1724108
| CAS No. | CATO-C4X-1724108 |
| Molecular Formula | C12H15FN2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Paliperidone Impurity 108 HCl (C12H15FN2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Paliperidone Impurity 108 HCl (CAS CATO-C4X-1724108, C12H15FN2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Paliperidone Impurity 108 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15FN2O HCl |
| Molecular Weight | 258.72 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 16 (CAS 1006685-69-3)
- Paliperidone Impurity 49 (CAS 1008796-22-2)
- Paliperidone Impurity 46 (CAS 1008796-23-3)
- Paliperidone-d4 (CAS 1020719-55-4)
- Paliperidone Impurity 61 (CAS 1138463-56-5)
- Paliperidone Impurity 32 (CAS 1141761-80-9)
- Paliperidone Impurity 161 (CAS 1160611-32-4)
- Paliperidone Impurity 36 (CAS 1160915-55-8)
Recommended Standards
- Terbinafine EP Impurity E Dihydrochloride Salt (CAS 934365-23-8(free base))
- Nintedanib Impurity 8 (CAS 2410649-54-4)
- Cefazolin Impurity 78 (CAS CATO-C4X-157778)
- tert-Butyl 4-((bis(2-((3-chlorobenzyl)(cyclopropyl)amino)-2-oxoethyl)amino)methyl)piperidine-1-carboxylate (CAS 1353979-86-8)
- 3-Cyanopropane-1-sulfonamide (CAS 812691-80-8)
- 2-methyl-6-nitro-2H-indazole (CAS 6850-22-2)
- tert-Butyl ((2S,4S)-4-(4-methoxy-3-(3-methoxypropoxy)-benzyl)-5-methyl-1-oxohexan-2-yl)carbamate (CAS 172900-83-3)
- Galantamine hydrobromide (CAS 1953-04-4)
- Utatrectinib (CAS 1079274-94-4)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com