Paliperidone Impurity 4 CAS CATO-C4X-17244
| CAS No. | CATO-C4X-17244 |
| Molecular Formula | C19H19FN4O4 |
| Molecular Weight | 386.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Paliperidone Impurity 4 (CAS CATO-C4X-17244, C19H19FN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Paliperidone Impurity 4 (C19H19FN4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Paliperidone Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H19FN4O4 |
| Molecular Weight | 386.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Paliperidone Standards
- Paliperidone Impurity J (CAS 2379324-96-4)
- Paliperidone Impurity 92 (CAS CATO-C4X-172492)
- Paliperidone Impurity 94 (CAS CATO-C4X-172494)
- Paliperidone Impurity 42 (CAS 1380413-60-4)
- Paliperidone Impurity 25 (CAS CATO-C4X-172425)
- Paliperidone Impurity 119 (CAS CATO-C4X-1724119)
- Paliperidone Impurity 63 (CAS 1268058-08-7)
- Paliperidone Impurity 11 (CAS 531524-17-1)
Recommended Standards
- 2-Pyridyl-2,8-bis(trifluoromethyl)-4-quinolyl ketone; [2,8-bis(Trifluoromethyl)-4-quinolyl]-2-pyridyl ketone; 2-Pyridinyl[2,8-bis(trifluoromethyl)-4-quinolinyl]methanone 35853-55-5 AB1006526 (CAS 35853-55-5)
- 7-Phenyl-3-(3-(trifluoromethyl)benzyl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1105224-80-3)
- 5-[[3-Methoxy-4-[(4-nitrophenyl)methoxy]phenyl]methylene]thiazolidine-2,4-dione (CAS 331660-78-7)
- 1-(3,4-Dimethoxybenzyl)-3-(4-(trifluoromethoxy)phenyl)thiourea (CAS 1119391-84-2)
- Nitrofurantoin Impurity 2 (CAS 777-34-4)
- Tolvaptan Impurity 35 (CAS CATO-C4X-195535)
- Tetrabenazine Impurity 58 (CAS CATO-C4X-274858)
- Revefenacin (CAS 864750-70-9)
- 5-Cyano-2-hydroxy-6-methylnicotinic acid (CAS 50617-56-6)
- 2-Bromo-3-(4-methylphenyl)propanenitrile (CAS 62448-29-7)
- 5-Phenylbenzo[d]thiazol-2-amine (CAS 1208394-99-3)
- 2-Bromo-5-(phenoxymethyl)pyridine (CAS 845973-23-1)
- 7-Methyl-2H-pyrazolo[3,4-d]pyridazin-4-ol (CAS 59515-06-9)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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