Paliperidone Impurity 63 CAS 1268058-08-7
| CAS No. | 1268058-08-7 |
| Molecular Formula | C22H25FN4O3 |
| Molecular Weight | 412.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Paliperidone Impurity 63.
CATO supplies Paliperidone Impurity 63 (CAS 1268058-08-7), a pharmacopoeial impurity reference standard (molecular formula C22H25FN4O3, MW 412.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H25FN4O3, Paliperidone Impurity 63 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 412.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Paliperidone Impurity 63 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H25FN4O3 |
| Molecular Weight | 412.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Paliperidone Standards
- Paliperidone Impurity 119 (CAS CATO-C4X-1724119)
- Paliperidone Impurity 42 (CAS 1380413-60-4)
- Paliperidone Impurity 11 (CAS 531524-17-1)
- Paliperidone Impurity 59 (CAS 766485-15-8)
- Paliperidone Impurity 87 (CAS CATO-C4X-172487)
- Paliperidone Impurity 1 （Mixture of Tautomeric Isomers） (CAS 1189516-65-1)
- Paliperidone Impurity 69 (CAS CATO-C4X-172469)
- Paliperidone Impurity 26 (CAS CATO-C4X-172426)
Recommended Standards
- Meropenem Impurity 36 (CAS CATO-C4X-130936)
- Roxadustat Impurity 145 (CAS CATO-C4X-2213145)
- Meropenem impurity 29 (CAS CATO-C4X-130929)
- Toceranib impurity 2 (CAS CATO-C4X-25852)
- Difluprednate Impurity 1 (CAS CATO-C4X-21781)
- Cefdinir Impurity 81 (CAS 137171-77-8)
- Mirabegron Impurity 135 (CAS CATO-C4X-1032135)
- Potassium trifluoro(2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)borate (CAS 1403991-19-4)
- 5-Amino-2-(aminomethyl)phenol (CAS 133914-70-2)
- Carnitine Chloride Impurity 3 (CAS 117604-42-9)
- Nifuroxazide-d4 (CAS 1188487-83-3)
- Sofosbuvir Impurity 3 (CAS CATO-C4X-10523)
- 5-(2,3-Dichlorophenoxy)furan-2-carbaldehyde (CAS 1291489-24-1)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com