Pazopanib Impurity 32 CAS CATO-C4X-172532
| CAS No. | CATO-C4X-172532 |
| Molecular Formula | C21H23N7O2S |
| Molecular Weight | 437.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Pazopanib Impurity 32 (CAS CATO-C4X-172532, C21H23N7O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Pazopanib Impurity 32 (C21H23N7O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 437.52 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Pazopanib Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H23N7O2S |
| Molecular Weight | 437.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Pazopanib Standards
- Pazopanib (CAS 444731-52-6)
- Pazopanib Impurity 55 (CAS CATO-C4X-172555)
- Pazopanib Impurity 62 (CAS CATO-C4X-172562)
- Pazopanib Impurity 65 (CAS CATO-C4X-172565)
- Pazopanib Impurity 43 (CAS CATO-C4X-172543)
- Pazopanib Impurity 53 (CAS CATO-C4X-172553)
- Pazopanib-d3 Hydrochloride (CAS CATO-CCAD304303)
- Pazopanib-d6 (CAS 1219592-01-4)
Recommended Standards
- Mycophenolate Mofetil-d4 (CAS 1132748-21-0)
- Ziprasidone Impurity 46 (CAS 2369664-19-5)
- Fluphenazine Decanoate EP Impurity B (CAS 69-23-8)
- Tafluprost Ethyl Amide (CAS 1185851-52-8)
- Enzalutamide Impurity 19 (CAS 73792-08-2)
- Dyclonine Impurity 32 (CAS 35922-84-0)
- Gentamicin Impurity 9 (CAS 287916-51-2 (free base))
- 5-(Hydroxymethyl)-3-(trifluoromethyl)pyridin-2(1H)-one (CAS 1378689-13-4)
- 2-(5-fluorofuran-2-yl)acetic acid (CAS 1522468-17-2)
- Oxazolo[5,4-c]pyridine-6-carboxylic acid (CAS 478169-55-0)
- (1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-penten-3-one Oxime (CAS 1170613-55-4)
- 6-(4-Nitro-1H-pyrazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 482574-67-4)
- 2-Chloro-1-(1,2,6-trimethyl-1H-indol-3-yl)ethan-1-one (CAS 843638-37-9)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
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