Enzalutamide Impurity 19 CAS 73792-08-2
| CAS No. | 73792-08-2 |
| Molecular Formula | C8H8FNO2 |
| Molecular Weight | 169.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Enzalutamide Impurity 19 (CAS 73792-08-2) is a certified pharmaceutical impurity reference standard with the molecular formula C8H8FNO2 and a molecular weight of 169.15 g/mol.
Based on its molecular formula C8H8FNO2, Enzalutamide Impurity 19 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 169.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8FNO2 |
| Molecular Weight | 169.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Enzalutamide Standards
- Enzalutamide Impurity N4 (CAS 869936-86-7)
- Enzalutamide Impurity 20 (CAS 1187368-67-7)
- Enzalutamide Impurity 21 (CAS 446-31-1)
- Enzalutamide Impurity 24 (CAS 403-24-7)
- Enzalutamide Impurity 22 (CAS 392-09-6)
- Enzalutamide Impurity 36 (CAS 208122-06-9)
- Enzalutamide Impurity 33 (CAS 934600-95-0)
- Enzalutamide Impurity 35 (CAS 888072-96-6)
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