Pazopanib Impurity 55 CAS CATO-C4X-172555
| CAS No. | CATO-C4X-172555 |
| Molecular Formula | C21H23N7O2S |
| Molecular Weight | 437.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Pazopanib Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Pazopanib Impurity 55 (CAS CATO-C4X-172555) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23N7O2S and a molecular weight of 437.52 g/mol.
The molecular framework of Pazopanib Impurity 55 (C21H23N7O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H23N7O2S |
| Molecular Weight | 437.52 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Pazopanib Standards
- Pazopanib (CAS 444731-52-6)
- Pazopanib Impurity 32 (CAS CATO-C4X-172532)
- Pazopanib Impurity 62 (CAS CATO-C4X-172562)
- Pazopanib Impurity 65 (CAS CATO-C4X-172565)
- Pazopanib Impurity 43 (CAS CATO-C4X-172543)
- Pazopanib Impurity 53 (CAS CATO-C4X-172553)
- Pazopanib-d3 Hydrochloride (CAS CATO-CCAD304303)
- Pazopanib-d6 (CAS 1219592-01-4)
Recommended Standards
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- Prednisolone Impurity 42 (CAS 3597-59-9)
- Ipragliflozin Impurity 2 (CAS CATO-C4X-18852)
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- Azathioprine EP Impurity G (Thiamiprine) (CAS 5581-52-2)
- (2-Amino-4-(isopropoxycarbonyl)phenyl)boronic acid hydrochloride (CAS 1150114-64-9)
- (R)-5-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolan-4-one (CAS 174563-88-3)
- N1-Cyclohexyl-N2-mesityloxalamide (CAS 941984-17-4)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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