Pemetrexed Impurity 59 HCl CAS CATO-C4X-172659
| CAS No. | CATO-C4X-172659 |
| Molecular Formula | C16H28N2O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Pemetrexed Impurity 59 HCl (C16H28N2O7HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Pemetrexed Impurity 59 HCl (CAS CATO-C4X-172659), a pharmacopoeial impurity reference standard (molecular formula C16H28N2O7HCl, MW 396.87 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pemetrexed Impurity 59 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H28N2O7 HCl |
| Molecular Weight | 396.87 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Pemetrexed Standards
- Pemetrexed Impurity 21 (CAS 1001-19-0)
- Pemetrexed Impurity 11 (CAS 100643-27-4)
- Pemetrexed Impurity 22 (CAS 1075-59-8)
- Pemetrexed Impurity 54 (CAS 1265908-58-4)
- Pemetrexed EP Impurity D Trisodium salt (CAS 1265908-59-5)
- Pemetrexed Impurity (CAS 1265908-60-8)
- Pemetrexed Impurity (CAS 1265908-61-9)
- Pemetrexed Impurity 53 (CAS 1320346-37-9)
Recommended Standards
- Thiotepa Impurity 6 (CAS CATO-C4X-21566)
- Aripiprazole Impurity 24 (CAS 952308-47-3)
- Gadodiamide Impurity 9 (CAS CATO-C4X-31439)
- 2-(3,4-Dichlorophenyl)-1H-imidazole-5-carboxylic acid (CAS 34626-07-8)
- 5-Methyl-N4-(thiazol-2-yl)isoxazole-3,4-dicarboxamide (CAS 338408-95-0)
- Cyclohexynebis(triphenylphosphine)platinum(0) (CAS 34872-50-9)
- 6-Bromo-2-morpholin-4-ylpyridin-3-amine (CAS 220499-47-8)
- Ritonavir EP Impurity F (CAS 1010809-61-6)
- 5-(3-methanesulfonylphenyl)pyridin-2-amine (CAS 1314987-83-1)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com