Rizatriptan EP Impurity B Chloride CAS CATO-C4X-17528
| CAS No. | CATO-C4X-17528 |
| Molecular Formula | C28H32N9 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rizatriptan EP Impurity B Chloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Rizatriptan EP Impurity B Chloride (CAS CATO-C4X-17528) is a certified pharmaceutical impurity reference standard with the molecular formula C28H32N9Cl and a molecular weight of 530.08 g/mol.
The molecular framework of Rizatriptan EP Impurity B Chloride (C28H32N9Cl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rizatriptan EP Impurity B Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H32N9 Cl |
| Molecular Weight | 530.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan impurity 01 (CAS 1030849-63-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
Recommended Standards
- Anagrelide Impurity 24 (CAS 147249-41-0)
- Brivaracetam Impurity 173 (CAS CATO-C4X-2007173)
- Ketoconazole Impurity 10 (CAS 70894-66-5)
- 3-(4-Nitro-1H-pyrazol-1-yl)propanoic acid (CAS 512810-21-8)
- 5-Methoxy-3-methylpicolinaldehyde (CAS 1256813-09-8)
- N-(4-(3,4-Dichlorophenyl)thiazol-2-yl)-2-phenoxyacetamide (CAS 476285-33-3)
- Ethyl 4-(cycloheptylamino)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 922090-64-0)
- (S,Z)-2-Isopropyl-5-methyl-9-methylenecyclodec-5-en-1-one (CAS 25645-19-6)
- 4-Fluoro-5-methylisoxazol-3(2H)-one (CAS 131573-78-9)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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