Doxylamine impurity 26 CAS CATO-C4X-178926
| CAS No. | CATO-C4X-178926 |
| Molecular Formula | C13H12ClN |
| Molecular Weight | 217.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.69 g/mol gives Doxylamine impurity 26 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Doxylamine impurity 26 (CAS CATO-C4X-178926, C13H12ClN) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Doxylamine impurity 26 (C13H12ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 217.69 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12ClN |
| Molecular Weight | 217.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Doxylamine Standards
- Doxylamine Impurity 1 (CAS 100393-43-9)
- Doxylamine Impurity N91 (CAS CATO-C1460291)
- Doxylamine EP Impurity B (CAS 19490-92-7)
- Doxylamine Hydrogen Succinate EP Impurity B (CAS CATO-C4X-178922)
- Doxylamine N,N-DiDesmethyl Impurity (CAS 78868-04-9)
- Doxylamine EP Impurity D (CAS 91-02-1)
- Doxylamine impurity 25 (CAS 15260-65-8)
- Doxylamine Impurity 17 (CAS 1221-70-1)
Recommended Standards
- Loratadine Impurity 92 (CAS CATO-C4X-142692)
- Baclofen-d4 (CAS 1189938-30-4)
- Chlorphenamine impurity 56 (CAS CATO-C4X-118856)
- 3-(5-Chlorothiophen-2-yl)-1,2,4-thiadiazol-5-amine (CAS 1153983-60-8)
- Butenafine Impurity 11 (CAS 110951-99-0)
- Desloratadine Impurity 34 (CAS CATO-C4X-143034)
- Xanomeline impurity 43 (CAS CATO-C4X-330143)
- 5-Bromo-N-(2-(piperazin-1-yl)ethyl)furan-2-carboxamide hydrochloride (CAS 1586611-08-6)
- Bicyclo[4.3.2]undecan-10-one (CAS 61244-56-2)
- 3-(5-Ethyl-1,2,4-oxadiazol-3-yl)benzoic Acid (CAS 859155-81-0)
- Butanoic acid, 4-(ethylamino)-4-oxo-3-[(1-oxododecyl)amino]-, (3S)- (CAS 2007921-26-6)
- 6-(Hydroxymethyl)picolinic acid (CAS 1197-10-0)
- 4-Chlorobenzyl carbamimidothioate hydrochloride (CAS 544-47-8)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
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