Ceftizoxime Impurity 87 CAS CATO-C4X-179387
| CAS No. | CATO-C4X-179387 |
| Molecular Formula | C12H12N4O4S2 |
| Molecular Weight | 340.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ceftizoxime Impurity 87 (CAS CATO-C4X-179387, C12H12N4O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ceftizoxime Impurity 87 (C12H12N4O4S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Ceftizoxime Impurity 87 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12N4O4S2 |
| Molecular Weight | 340.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Ceftizoxime Standards
- Ceftizoxime Impurity 11(E-isomer) (CAS 1684396-27-7)
- Ceftizoxime Impurity 74(isomers mixture) (CAS 94088-75-2)
- Ceftizoxime Impurity 81 (CAS CATO-C4X-179381)
- Ceftizoxime Impurity 60 (CAS CATO-C4X-179360)
- (Z)-Ceftizoxime Impurity 22 (CAS CATO-C4X-179322)
- (Z)-Ceftizoxime Impurity 52 (CAS CATO-C4X-179352)
- Ceftizoxime Impurity 65 (CAS CATO-C4X-179365)
- Ceftizoxime Impurity 8 (CAS 33477-97-3)
Recommended Standards
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- Ruxolitinib Impurity 73 (CAS CATO-C4X-205873)
- Epalrestat Impurity 3 (CAS 794510-29-5)
- Ioversol impurity 29 (CAS CATO-C4X-209129)
- Avanafil Impurity 102 DiHCl (CAS 73706-74-8)
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- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
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