Tenofovir Alafenamide Impurity 25 CAS CATO-C4X-179725
| CAS No. | CATO-C4X-179725 |
| Molecular Formula | C15H26N5O4P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tenofovir Alafenamide Impurity 25.
Tenofovir Alafenamide Impurity 25 (CAS CATO-C4X-179725) is a certified pharmaceutical impurity reference standard with the molecular formula C15H26N5O4PC4H4O4 and a molecular weight of 487.45 g/mol.
Tenofovir Alafenamide Impurity 25 (C15H26N5O4PC4H4O4) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tenofovir Alafenamide Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H26N5O4P C4H4O4 |
| Molecular Weight | 487.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Linagliptin Impurity 2 (CAS 2518331-40-1)
- Glutathione Impurity 6 Trisodium Salt (CAS CATO-C4X-11856)
- Salbutamol Impurity 99 (CAS 27475-09-8)
- Tert-butyl 1-methyl-2-oxo-6-azaspiro[3.4]Octane-6-carboxylate (CAS 2168990-05-2)
- N,N-Dimethyl-N-[(1-methyl-1H-indol-2-yl)-methyl]ethane-1,2-diamine (CAS 883527-14-8)
- 2-(4-Phenoxyphenyl)ethanamine Hydrochloride (CAS 106272-17-7)
- Saclofen (CAS 125464-42-8)
- 2-[(4-nitrophenyl)sulfanyl]ethan-1-ol (CAS 13287-76-8)
- ((2S,6S)-6-Methylmorpholin-2-yl)methanol hydrochloride (CAS 2243501-64-4)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
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