Tenofovir alafenamide Impurity 44 CAS CATO-C4X-179744
| CAS No. | CATO-C4X-179744 |
| Molecular Formula | C21H29N6O5P |
| Molecular Weight | 476.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tenofovir alafenamide Impurity 44 (C21H29N6O5P) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Tenofovir alafenamide Impurity 44 (CAS CATO-C4X-179744, C21H29N6O5P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tenofovir alafenamide Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H29N6O5P |
| Molecular Weight | 476.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 33 (CAS CATO-C4X-179733)
- Tenofovir alafenamide Impurity 42 (CAS 2053424-82-9)
- Tenofovir alafenamide Impurity 45 (CAS CATO-C4X-179745)
- Tenofovir alafenamide Impurity 52 (CAS 383365-04-6)
- Tenofovir alafenamide (CAS 379270-37-8)
- Tenofovir alafenamide Impurity 62 (CAS CATO-C4X-179762)
- Tenofovir alafenamide impurity 74 (CAS 2053424-88-5)
- Tenofovir alafenamide impurity 75 (CAS 379270-36-7)
Recommended Standards
- Azacitidine Impurity 89 (CAS 69350-76-1)
- 485821-70-3 A827564 [2-methyl-6-oxidanyl-4,5-bis(phenylcarbonyloxy)oxan-3-yl] benzoate benzoic acid (4,5-dibenzoyloxy-6-hydroxy-2-methyl-3-oxanyl) ester (CAS 485821-70-3)
- N,N’,N”-Tris(3-aminoquinolino)phosphoric triamide (CAS 2097565-50-7)
- Methyl 4-methyl-2-(4-methylbenzamido)-5-((3-(trifluoromethyl)phenyl)carbamoyl)thiophene-3-carboxylate (CAS 332923-98-5)
- Pilocarpine EP Impurity B Sodium Salt (CAS 92598-79-3)
- Ubrogepant Impurity 8 (CAS CATO-C4X-34028)
- Amlodipine Besylate EP Impurity F (CAS 140171-66-0)
- tert-Butyl(1R,3R)-3-aminocyclobutane-1-carboxylatehydrochloride (CAS 2173637-24-4)
- 4-(Hydroxymethyl)-2,6-dimethylpiperidine (CAS 1186319-08-3)
- N-Cyclopentyl-4-iodobenzamide (CAS 331435-50-8)
- N-Butyl-N-(2-chloroethyl)butan-1-amine Hydrochloride (CAS 4535-81-3)
- 6-Bromo-4-methyl-1,2-dihydronaphthalene (CAS 35943-87-4)
- 7-bromo-2-methylimidazo[1,2-a]pyridine (CAS 1194375-40-0)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com