Sofosbuvir Impurity 78 CAS CATO-C4X-105278
| CAS No. | CATO-C4X-105278 |
| Molecular Formula | C38H31N3O9 |
| Molecular Weight | 673.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Sofosbuvir Impurity 78 (C38H31N3O9) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Sofosbuvir Impurity 78 (CAS CATO-C4X-105278), a pharmacopoeial impurity reference standard (molecular formula C38H31N3O9, MW 673.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C38H31N3O9 |
| Molecular Weight | 673.67 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 83 (CAS CATO-C4X-105283)
- Sofosbuvir Impurity 52 (CAS CATO-C4X-105252)
- Sofosbuvir Impurity 56 (CAS 1496551-70-2)
- Sofosbuvir Impurity 88 (CAS 30361-19-4)
- Sofosbuvir Impurity 10 (CAS CATO-C4X-105210)
- Sofosbuvir Impurity 11 (CAS CATO-C4X-105211)
- Sofosbuvir Impurity 4 (CAS 874638-94-5)
- Sofosbuvir Impurity 5 (CAS CATO-C4X-10525)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com