Tenofovir alafenamide Impurity 9 CAS CATO-C4X-17979
| CAS No. | CATO-C4X-17979 |
| Molecular Formula | C21H29N6O5P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tenofovir alafenamide Impurity 9 (CAS CATO-C4X-17979), a pharmacopoeial impurity reference standard (molecular formula C21H29N6O5PC4H4O4, MW 592.55 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tenofovir alafenamide Impurity 9 (C21H29N6O5PC4H4O4) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H29N6O5P C4H4O4 |
| Molecular Weight | 592.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Gamithromycin Impurity 1 (CAS 1797448-01-1)
- Vardenafil Impurity 37 (CAS CATO-C4X-101737)
- Imipenem Impurity 129 (CAS CATO-C4X-1662129)
- H-D-allo-Thr-OMe · HCl (CAS 60538-18-3)
- Danazol Impurity 31 (CAS 162070-22-6)
- Trans-4-(Acetamidomethyl)cyclohexanecarboxylic Acid (CAS 20704-66-9)
- Ethyl 5-aminoquinoline-2-carboxylate (CAS 1447608-15-2)
- 3-Bromo-2-(4,4-difluoropiperidin-1-yl)nitrobenzene (CAS 1707581-00-7)
- 4'-Fluoro-[1,1'-biphenyl]-3-thiol (CAS 141106-53-8)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com