Tenofovir alafenamide Impurity 91 CAS CATO-C4X-179791
| CAS No. | CATO-C4X-179791 |
| Molecular Formula | C18H26N10O7P2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tenofovir alafenamide Impurity 91 (CAS CATO-C4X-179791), a pharmacopoeial impurity reference standard (molecular formula C18H26N10O7P2C6H15N, MW 657.61 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tenofovir alafenamide Impurity 91 (C18H26N10O7P2C6H15N) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Tenofovir alafenamide Impurity 91 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H26N10O7P2 C6H15N |
| Molecular Weight | 657.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 11 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Elagolix Impurity 58 (CAS CATO-C4X-206858)
- Macitentan Impurity 46 (CAS CATO-C4X-117546)
- LCZ-696 Impurity 74 (CAS CATO-C4X-169674)
- 5-(([1,1'-biphenyl]-2-yloxy)methyl)-4-(2-methoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 722465-89-6)
- Racecadotril EP Impurity D (CAS 123658-06-0)
- Tert-butyl 3-(2-aminoethoxy)piperidine-1-carboxylate (CAS 1353987-73-1)
- 4-(4-Iodobenzoyl)-2-methylpyridine (CAS 1187169-63-6)
- 4-Ethoxy-2-naphthoic acid (CAS 1368864-77-0)
- 1-((5-Methylthiophen-2-yl)methyl)piperidin-4-amine (CAS 1092276-45-3)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com