Miconazole EP Impurity E CAS CATO-C4X-18025
| CAS No. | CATO-C4X-18025 |
| Molecular Formula | C22H21Cl4N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Miconazole EP Impurity E (CAS CATO-C4X-18025) is a certified pharmaceutical impurity reference standard with the molecular formula C22H21Cl4N2O3Br and a molecular weight of 583.12 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, Miconazole EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 583.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Miconazole EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21Cl4N2O3 Br |
| Molecular Weight | 583.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Miconazole Standards
- Miconazole-d5 Nitrate (CAS 1216653-51-8)
- Miconazole EP Impurity H (CAS 181931-30-6)
- Miconazole EP Impurity H (CAS 181931-30-6（free base）)
- Miconazole Impurity H nitarte salt (CAS 203264-09-9)
- Miconazole Nitrate (CAS 228321-87-7)
- Miconazole (CAS 22916-47-8)
- Miconazole EP Impurity D (CAS 24168-96-5)
- Miconazole EP Impurity I (CAS 24169-00-4)
Recommended Standards
- Oxacillin Impurity 20 HCI (CAS CATO-C4X-232120)
- Tofacitinib Impurity 225 (CAS 2026634-40-0)
- Mivacurium chloride Impurity 74 (CAS CATO-C4X-137574)
- 2-(2-Bromo-5-nitrophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244086-67-5)
- 4,9,11-Trioxatetracyclo[5.3.1.0(2,6).0(8,10)]undecan-3-one (CAS 632339-23-2)
- 2-Isopropoxy-3-pyridinol (CAS 1231977-15-3)
- (6-Methyl-3-(methylthio)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl 2-(2-methoxyphenoxy)acetate (CAS 877648-47-0)
- 2,5-Dioxopyrrolidin-1-yl 6-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoate (CAS 1219212-66-4)
- 2-(3,5-Dichlorophenoxy)-4-methoxypyridine-3-carbonitrile (CAS 339016-78-3)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com