Pranoprofen Impurity 45 CAS CATO-C4X-181145
| CAS No. | CATO-C4X-181145 |
| Molecular Formula | C15H12ClNO3 |
| Molecular Weight | 289.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pranoprofen Impurity 45 (C15H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Pranoprofen Impurity 45 (CAS CATO-C4X-181145) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12ClNO3 and a molecular weight of 289.71 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pranoprofen Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12ClNO3 |
| Molecular Weight | 289.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pranoprofen Standards
- Pranoprofen Impurity 19 (CAS CATO-C4X-181119)
- Pranoprofen Impurity 60 (CAS 111541-71-0)
- Pranoprofen impurity 69 (CAS CATO-C4X-181169)
- Pranoprofen Impurity 18 (CAS CATO-C4X-181118)
- Pranoprofen Impurity 28 (CAS CATO-C4X-181128)
- Pranoprofen Impurity 51 (CAS CATO-C4X-181151)
- Pranoprofen Impurity 71 (CAS CATO-C4X-181171)
- Pranoprofen Impurity 83 (CAS CATO-C4X-181183)
Recommended Standards
- Ketorolac impurity 69 (CAS 66635-89-0)
- 760192-98-1 Ethyl 4-(2-chloropyridine-3-carbonyl)benzoate DTXSID20641777 (CAS 760192-98-1)
- Bromfenac Impurity 72 (CAS 61941-63-7)
- N-benzyl-7-chlorobenzo[d][1,3]dioxole-5-carboxamide (CAS 930521-57-6)
- Vonoprazan Fumarate Impurity 45 (CAS 928325-82-0)
- Gadoteridol Impurity 23 (CAS CATO-C4X-225723)
- Gemcitabine Impurity 13 (CAS CATO-C4X-137213)
- 2-Bromo-6-methoxy-4-{[(1-methyl-1H-pyrazol-4-yl)amino]methyl}phenol (CAS 1153978-92-7)
- methyl 3-(1-ethyl-1H-pyrazol-4-yl)but-2-enoate (CAS 1563994-30-8)
- 5-Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarboxylic Acid Methyl Ester (CAS 72242-31-0)
- 3-((5-Methylpyridin-2-yl)oxy)aniline (CAS 901920-02-3)
- 4-Cyano-3,5-difluorophenyl 4-pentyl-benzoate (CAS 123843-69-6)
- 3-Amino-1,5-diimino-1,5-dihydropyrazolo[1,2-a][1,2,4]triazole-6-carboxylic acid (CAS 121447-39-0)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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