Bromfenac Impurity 72 CAS 61941-63-7
| CAS No. | 61941-63-7 |
| Molecular Formula | C15H12ClNO3 |
| Molecular Weight | 289.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Bromfenac Impurity 72 (CAS 61941-63-7, C15H12ClNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bromfenac Impurity 72 (C15H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Bromfenac Impurity 72 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12ClNO3 |
| Molecular Weight | 289.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bromfenac Standards
- Bromfenac Impurity 13 (CAS CATO-C4X-200213)
- Bromfenac Impurity 31 (CAS 71969-36-3)
- Bromfenac Impurity 52 (CAS CATO-C4X-200252)
- Bromfenac Impurity 53 (CAS 91714-50-0)
- Bromfenac Impurity 62 (CAS CATO-C4X-200262)
- Bromfenac Impurity 71 (CAS CATO-C4X-200271)
- Bromfenac Impurity 79 (CAS CATO-C4X-200279)
- Bromfenac Impurity 28 (CAS 91714-41-9)
Recommended Standards
- Pranoprofen impurity 69 (CAS CATO-C4X-181169)
- Oxazepam impurity 3 (CAS 5628-03-5)
- Pranoprofen Impurity 60 (CAS 111541-71-0)
- Oxazepam impurity 9 (CAS CATO-C4X-30909)
- Edoxaban Impurity N82 (CAS 165948-23-2)
- Tryptophan EP Impurity L Lithium Salt (Mixture of Diastereomers) (CAS 287170-99-4 (Free Acid))
- Loxoprofen Impurity 11 (CAS 81762-92-7)
- 1,3-diethyl 2-(cyclohex-2-en-1-yl)propanedioate (CAS 6305-63-1)
- Nefopam Impurity 4 (CAS 32557-55-4)
- Docetaxel Impurity 12 (CAS 158810-73-2)
- 4-chlorofuran-2-carboxylic acid (CAS 4303-17-7)
- 1-(Isochroman-3-yl)-N-methylmethanamine hydrochloride (CAS 1820665-24-4)
- N-(2-(Dimethylamino)ethyl)-N-(tetrahydro-2H-pyran-4-yl)-1-naphthamide (CAS 1797962-02-7)
- Hexapeptide-11 (CAS 100684-36-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com