Suvorexant Impurity 49 CAS CATO-C4X-181249
| CAS No. | CATO-C4X-181249 |
| Molecular Formula | C26H28N8O2 |
| Molecular Weight | 484.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Suvorexant Impurity 49 (C26H28N8O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Suvorexant Impurity 49 (CAS CATO-C4X-181249) is a certified pharmaceutical impurity reference standard with the molecular formula C26H28N8O2 and a molecular weight of 484.55 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Suvorexant Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H28N8O2 |
| Molecular Weight | 484.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Suvorexant Standards
- Suvorexant Impurity 45 (CAS 1030377-39-9)
- Suvorexant Impurity 7 (CAS CATO-C4X-18127)
- Suvorexant Impurity 5 (CAS 2762965-04-6)
- Suvorexant Impurity 20 (CAS CATO-C4X-181220)
- Suvorexant Impurity 6 (CAS CATO-C4X-18126)
- Suvorexant Impurity 22 (CAS CATO-C4X-181222)
- 【禁售不询】Suvorexant (CAS 1030377-33-3)
- Suvorexant Impurity 1 (CAS 1030377-80-0)
Recommended Standards
- Fluticasone Propionate EP Impurity B (CAS 948566-12-9)
- Avacopan Impurity 4 (CAS 1346623-05-9)
- Vilazodone impurity 15 (CAS 2970582-50-2)
- Lobeglitazone-d4 (CAS CATO-CCAD304334)
- Dotinurad Impurity 203 (CAS CATO-C4X-2494203)
- Linezolid Impurity 57 (CAS 477846-96-1)
- Cyclophosphamide impurity 32 (CAS CATO-C4X-230632)
- 2-(1,4-Diazepan-1-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1774897-48-1)
- Methyl 2-(4-chloro-2-formylphenoxy)propanoate (CAS 1149804-15-8)
- 2-(2,4-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene (CAS 898778-88-6)
- 5-Ethylthiophene-3-sulfonyl chloride (CAS 1245823-95-3)
- (+)-Geosmin (CAS 104873-46-3)
- 4-(Cyanomethyl)benzo[d]oxazole-2-sulfonyl chloride (CAS 1803741-42-5)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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