Cobicistat impurity 8 CAS CATO-C4X-18168

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-18168
Molecular FormulaC16H27N3O6S2
Molecular Weight421.53 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cobicistat impurity 8 CAS CATO-C4X-18168 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 421.53 g/mol gives Cobicistat impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Cobicistat impurity 8 (CAS CATO-C4X-18168), a pharmacopoeial impurity reference standard (molecular formula C16H27N3O6S2, MW 421.53 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C16H27N3O6S2, Cobicistat impurity 8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 421.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H27N3O6S2
Molecular Weight421.53 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3
Sulfur Atoms2

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