Cobicistat Impurity N1 CAS 1247119-35-2
| CAS No. | 1247119-35-2 |
| Molecular Formula | C19H32N4O4S |
| Molecular Weight | 412.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Cobicistat Impurity N1 (CAS 1247119-35-2), a pharmacopoeial impurity reference standard (molecular formula C19H32N4O4S, MW 412.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Cobicistat Impurity N1 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H32N4O4S |
| Molecular Weight | 412.55 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cobicistat Standards
- Cobicistat impurity 8 (CAS CATO-C4X-18168)
- Cobicistat impurity (CAS 1004316-92-0)
- Cobicistat impurity 7 (CAS 1004316-93-1)
- Cobicistat impurity 6 (CAS 1370406-84-0)
- Cobicistat impurity 14 (CAS 1051463-15-0)
- Cobicistat (CAS 1004316-88-4)
- Cobicistat Impurity 3 (CAS 1051463-82-1)
- Cobicistat Impurity 4 (CAS 2230789-82-7)
Recommended Standards
- Tirofiban Impurity 69 (CAS CATO-C4X-125469)
- Cinalukast (CAS 128312-51-6)
- Tirofiban Impurity 58 (CAS CATO-C4X-125458)
- 2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-7-[(Z)-2-[4-(propan-2-yl)phenyl]ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 303986-69-8)
- Levosimendan Impurity 12 (CAS CATO-C4X-130812)
- Posaconazole impurity 236 (CAS CATO-C4X-1208236)
- Dapoxetine Impurity 13 (CAS 94305-25-6)
- 1H-Imidazole-2-sulfinic acid (CAS 160291-68-9)
- 2,2,7,7-tetramethyl-octane-3,6-diol (CAS 337959-46-3)
- Pyrrolidin-3-ylmethyl trifluoromethanesulfonate (CAS 1337880-78-0)
- (E)-4-(3-Oxo-3-(4-propoxyphenyl)prop-1-en-1-yl)benzoic acid (CAS 2651958-58-4)
- 3-(5-Methyl-2h-tetrazol-2-yl)adamantane-1-carbohydrazide (CAS 438219-64-8)
- 3-(4-(Difluoromethoxy)phenyl)-2-mercaptoquinazolin-4(3h)-one (CAS 380340-06-7)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com