Lobeline Impurity 12 CAS CATO-C4X-181812
| CAS No. | CATO-C4X-181812 |
| Molecular Formula | C22H26ClNO |
| Molecular Weight | 355.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lobeline Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Lobeline Impurity 12 (CAS CATO-C4X-181812), a pharmacopoeial impurity reference standard (molecular formula C22H26ClNO, MW 355.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Lobeline Impurity 12 (C22H26ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H26ClNO |
| Molecular Weight | 355.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lobeline Standards
- Lobeline impurity 18 (CAS CATO-C4X-181818)
- Lobeline Impurity 13 (CAS CATO-C4X-181813)
- Lobeline impurity 15 (CAS CATO-C4X-181815)
- Lobeline impurity 16 (CAS 2469224-15-3)
- Lobeline EP Impurity C (CAS CATO-C4X-181821)
- Lobeline Hydrochloride EP Impurity A (CAS CATO-C4X-18181)
- Lobeline impurity 22 (CAS CATO-C4X-181822)
- Lobeline Impurity 4 (CAS CATO-C4X-18184)
Recommended Standards
- 3,6-Diiodopicolinonitrile (CAS 827616-53-5)
- 3,5-Diiodoisonicotinonitrile (CAS 827616-50-2)
- Sibutramine Impurity 8 (CAS CATO-C4X-18538)
- 2,4-Diiodonicotinonitrile (CAS 827616-54-6)
- Aclidinium bromide Impurity 2 (CAS 7333-07-5)
- Finerenone Impurity 272 (CAS 2385902-88-3)
- Levocetirizine Impurity 68 (CAS CATO-C4X-108368)
- 1-(3-Bromofuran-2-yl)-2,2,2-trifluoroethanone (CAS 1343152-18-0)
- 3-Amino-N-(benzyloxycarbonyl)-L-alanine methyl ester hydrochloride (CAS 35761-27-4)
- 5-(1-(2,3-Dimethylphenoxy)ethyl)-1,3,4-thiadiazol-2-amine (CAS 842973-77-7)
- 1-(4-Fluorobenzyl)-1,4-dihydropyrazine-2,3-dione (CAS 1031557-43-3)
- 3-Benzoyl-5-benzylidene-2-mercapto-3,5-dihydro-imidazol-4-one (CAS 7245-67-2)
- Methyl 2-(4-hydroxymethylphenoxy)acetate (CAS 117048-44-9)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
Why CATO?
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