Lobeline Impurity 4 CAS CATO-C4X-18184
| CAS No. | CATO-C4X-18184 |
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lobeline Impurity 4 (CAS CATO-C4X-18184, C22H27NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H27NO2, Lobeline Impurity 4 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 337.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Lobeline Standards
- Lobeline Hydrochloride EP Impurity A (CAS CATO-C4X-18181)
- Lobeline impurity 22 (CAS CATO-C4X-181822)
- Lobeline impurity 6 (CAS CATO-C4X-18186)
- Lobeline Impurity 13 (CAS CATO-C4X-181813)
- Lobeline impurity 15 (CAS CATO-C4X-181815)
- Lobeline impurity 16 (CAS 2469224-15-3)
- Lobeline EP Impurity C (CAS CATO-C4X-181821)
- Lobeline Impurity 2 (CAS 579-21-5)
Recommended Standards
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- Ozanimod Impurity 26 (CAS CATO-C4X-290226)
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- Progesterone Impurity 65 (CAS CATO-C4X-150265)
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- DBCO-NHS ester 3 (CAS 1393350-27-0)
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- 2-Chloro-6-(pyrrolidin-1-yl)pyridine (CAS 117362-51-3)
- 5,7-Difluoroindoline-2,3-dione (CAS 116570-41-3)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
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