Lobeline impurity 18 CAS CATO-C4X-181818
| CAS No. | CATO-C4X-181818 |
| Molecular Formula | C22H26ClNO |
| Molecular Weight | 355.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lobeline impurity 18 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Lobeline impurity 18 (CAS CATO-C4X-181818, C22H26ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lobeline impurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 355.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lobeline impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H26ClNO |
| Molecular Weight | 355.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lobeline Standards
- Lobeline Impurity 12 (CAS CATO-C4X-181812)
- Lobeline Impurity 13 (CAS CATO-C4X-181813)
- Lobeline impurity 15 (CAS CATO-C4X-181815)
- Lobeline impurity 16 (CAS 2469224-15-3)
- Lobeline EP Impurity C (CAS CATO-C4X-181821)
- Lobeline Hydrochloride EP Impurity A (CAS CATO-C4X-18181)
- Lobeline impurity 22 (CAS CATO-C4X-181822)
- Lobeline Impurity 4 (CAS CATO-C4X-18184)
Recommended Standards
- Sibutramine Impurity 8 (CAS CATO-C4X-18538)
- 3,6-Diiodopicolinonitrile (CAS 827616-53-5)
- 1,2-diiodocubane (CAS 116503-45-8)
- 3,5-Diiodoisonicotinonitrile (CAS 827616-50-2)
- Mivacurium Chloride Impurity 14 (CAS 107740-64-7)
- Naloxone Impurity 18 (CAS CATO-C4X-149318)
- Pirarubicin Impurity 4 (CAS CATO-C4X-24684)
- N-(N-Heptyl)-5-chloro-1-naphthalenesulfonamide (CAS 102649-79-6)
- 4-Methoxy-1H-pyrrolo[2,3-c]pyridine (CAS 357263-40-2)
- 2-Bromo-6,6-dimethyl-4,5,6,7-tetrahydro-1,3-benzothiazole (CAS 1369135-69-2)
- 1-fluoro-2-methoxy-4-nitro-5-(trifluoromethyl)benzene (CAS 863983-95-3)
- 4-fluoro-3-(propan-2-yl)aniline (CAS 710351-86-3)
- 2-Phenyl-2H-1,2,3-triazole-4-carbonyl chloride (CAS 36386-85-3)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com