Lobeline impurity 6 CAS CATO-C4X-18186
| CAS No. | CATO-C4X-18186 |
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lobeline impurity 6 (CAS CATO-C4X-18186, C22H27NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lobeline impurity 6 (C22H27NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Lobeline impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27NO2 |
| Molecular Weight | 337.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Lobeline Standards
- Lobeline Hydrochloride EP Impurity A (CAS CATO-C4X-18181)
- Lobeline impurity 22 (CAS CATO-C4X-181822)
- Lobeline Impurity 4 (CAS CATO-C4X-18184)
- Lobeline Impurity 13 (CAS CATO-C4X-181813)
- Lobeline impurity 15 (CAS CATO-C4X-181815)
- Lobeline impurity 16 (CAS 2469224-15-3)
- Lobeline EP Impurity C (CAS CATO-C4X-181821)
- Lobeline Impurity 2 (CAS 579-21-5)
Recommended Standards
- Danazol (CAS 17230-88-5)
- 4-Chloro-2-iodo-6-(trifluoromethoxy)aniline (CAS 1000802-17-4)
- 3-Chloro-2-iodo-4-(trifluoromethoxy)aniline (CAS 1792885-92-7)
- Tofacitinib Impurity 65 (CAS CATO-C4X-107965)
- Iopamidol Impurity 34 (CAS CATO-C4X-145034)
- Nicardipine Impurity 36 (CAS 115972-93-5)
- Clenbuterol EP impurity D (CAS 99-92-3)
- H-D-Chg-OH.HCl (CAS 61367-40-6)
- rac-[(2R,3S)-1-cyclopropyl-2-(1-methyl-1H-imidazol-5-yl)piperidin-3-yl]methanamine (CAS 1969288-75-2)
- Tafamidis Impurity 1 (CAS 1184581-58-5)
- 1-(2,2-Difluoroethyl)-4-iodo-5-methyl-1H-pyrazol-3-amine (CAS 1354706-79-8)
- N-(4-(N-(2-bromoethyl)sulfamoyl)phenyl)acetamide (CAS 78234-01-2)
- 4-Amino-3-(ethylamino)benzonitrile (CAS 467235-09-2)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com