Letrozole Impurity 3 CAS CATO-C4X-18293

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-18293
Molecular FormulaC17H13N5O
Molecular Weight303.32 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Letrozole Impurity 3 CAS CATO-C4X-18293 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 303.32 g/mol gives Letrozole Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Letrozole Impurity 3 (CAS CATO-C4X-18293) is a certified pharmaceutical impurity reference standard with the molecular formula C17H13N5O and a molecular weight of 303.32 g/mol.

Based on its molecular formula C17H13N5O, Letrozole Impurity 3 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 303.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Letrozole Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H13N5O
Molecular Weight303.32 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms5

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