Ivacaftor impurity 17 CAS CATO-C4X-296417
| CAS No. | CATO-C4X-296417 |
| Molecular Formula | C10H6N2O4 |
| Molecular Weight | 218.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ivacaftor impurity 17 (CAS CATO-C4X-296417, C10H6N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ivacaftor impurity 17 (C10H6N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 218.17 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ivacaftor impurity 17 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6N2O4 |
| Molecular Weight | 218.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Ivacaftor Standards
- Ivacaftor Impurity 7 (CAS 52980-28-6)
- Ivacaftor Impurity 9 (CAS 26892-90-0)
- Ivacaftor Impurity 10 (CAS 873055-58-4)
- Ivacaftor Impurity 12 (CAS CATO-C4X-296412)
- Ivacaftor Impurity 11 (CAS 13721-01-2)
- Ivacaftor Impurity 3 (CAS 873055-57-3)
- Ivacaftor Impurity 14 (CAS 54535-22-7)
- Ivacaftor Impurity 13 (CAS 529-37-3)
Recommended Standards
- 2-((3-(Trifluoromethyl)phenoxy)methyl)oxirane (CAS 585-45-5)
- Atogepant Impurity 20 (CAS 1456803-49-8)
- Cinacalcet Impurity 34 (CAS 53473-36-2)
- 3-Cyclopropyl-1-(2,2,2-trifluoroethyl)-1h-pyrazole-4-carbaldehyde (CAS 1006462-81-2)
- Eldecalcitol Impurity 62 (CAS CATO-C4X-214062)
- Budesonide Impurity 33 (CAS 23825-05-0)
- Selumetinib Impurity 17 (CAS CATO-C4X-305317)
- 2-(Pentan-2-ylamino)acetic acid (CAS 87045-12-3)
- 3-[7-(1-methyl-1h-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid (CAS 1170616-38-2)
- 4-(4-Hydroxyphenyl)-3,6-dihydropyridine-1(2H)-carboxamide (CAS 923215-70-7)
- Diltiazem Impurity N29 Hydrochloride (CAS 42399-54-2)
- 3-(Chloromethyl)pyridin-4-amine (CAS 887584-31-8)
- N2-Methylpyridine-2,3-diamine dihydrochloride (CAS 1197617-33-6)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com