Torasemide Impurity 42 CAS CATO-C4X-183642

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-183642
Molecular FormulaC16H19N5O4S
Molecular Weight377.42 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Torasemide Impurity 42 CAS CATO-C4X-183642 chemical structure

Description

Torasemide Impurity 42 (CAS CATO-C4X-183642) is a certified pharmaceutical impurity reference standard with the molecular formula C16H19N5O4S and a molecular weight of 377.42 g/mol.

Torasemide Impurity 42 (C16H19N5O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H19N5O4S
Molecular Weight377.42 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms5
Sulfur Atoms1

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