Articaine EP Impurity H HCl CAS 2602451-77-2
| CAS No. | 2602451-77-2 |
| Molecular Formula | C16H26N2O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Articaine EP Impurity H HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Articaine EP Impurity H HCl (CAS 2602451-77-2), a pharmacopoeial impurity reference standard (molecular formula C16H26N2O3SHCl, MW 362.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Articaine EP Impurity H HCl (C16H26N2O3SHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H26N2O3S HCl |
| Molecular Weight | 362.91 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Articaine Standards
- Articaine EP Impurity B (CAS 114176-52-2)
- Articaine EP Impurity B HCl (CAS 114176-52-2(Free Base))
- Articaine EP Impurity J (CAS 1160919-46-9)
- Articaine Impurity N21 (CAS 13781-65-2)
- Articaine impurity 01 (CAS 161448-93-7)
- Articaine impurity 17 HCl (CAS 161449-05-4)
- Articaine EP Impurity A (CAS 1712677-79-6)
- Articaine EP Impurity A HCl (CAS 1712677-79-6(free base))
Recommended Standards
- Avanafil Impurity 4 (CAS 1452128-53-8)
- Efinaconazole Impurity 20 (CAS 2055038-60-1)
- Faropenem Impurity 18 (CAS CATO-C4X-128918)
- 3,6-Dichloro-2-(trifluoromethyl)pyridine (CAS 89719-91-5)
- 5-Pyrimidin-2-ylthiophene-2-carboxylic acid (CAS 656226-79-8)
- Ethyl 1-(2,2-difluoroethyl)-3-nitro-1H-pyrazole-5-carboxylate (CAS 1384856-19-2)
- 6-((3-(Trifluoromethyl)benzyl)thio)imidazo[2,1-b]thiazole-5-carbaldehyde (CAS 303996-46-5)
- (4-(dimethylamino)phenyl)boronic acid (CAS 28611-39-4)
- Ethyl 2-Amino-4,5,6,7-tetrahydrobenzothiazole-6-carboxylate (CAS 134136-00-8)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com