Thiamine /Vitamin B1 Impurity 28 CAS CATO-C4X-187328
| CAS No. | CATO-C4X-187328 |
| Molecular Formula | C9H15N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Thiamine /Vitamin B1 Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Thiamine /Vitamin B1 Impurity 28 (CAS CATO-C4X-187328, C9H15N3O2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Thiamine /Vitamin B1 Impurity 28 (C9H15N3O2SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C9H15N3O2S 2*HCl |
| Molecular Weight | 265.76 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Thiamine Standards
- Thiamine Impurity 30 (CAS 100502-51-0)
- Thiamine Nitrate EP Impurity G (CAS 1037-29-2)
- Thiamine Impurity 11 (CAS 105070-51-7)
- Thiamine /Vitamin B1 Impurity 50 (CAS 10553-88-5)
- Thiamine /Vitamin B1 Impurity 54 Ammonium Salt (CAS 10553-88-5 (free form))
- Thiamine EP Impurity F (CAS 10593-44-9)
- Thiamine disulfide (dinitrate) (CAS 109125-52-2)
- Thiamine Impurity 54 (CAS 1124-01-2)
Recommended Standards
- Dapagliflozin Impurity 42 (CAS CATO-C4X-113842)
- Resmetirom impurity 129 (CAS CATO-C4X-2912129)
- Olaparib impurity 141 (CAS CATO-C4X-1135141)
- 5-Methylpyrazine-2,3(1H,4H)-dithione (CAS 87256-74-4)
- 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)azetidin-2-one (CAS 2369772-35-8)
- 2-Amino-5-(ethylsulfonyl)-4-(4-methoxyphenyl)thiophene-3-carbonitrile (CAS 1713714-29-4)
- Octylpyridinium bromide (CAS 2534-66-9)
- 2-(2-Fluorophenyl)-6-(trifluoromethyl)pyridin-3-amine (CAS 1214334-88-9)
- 2-{1H-pyrrolo[2,3-c]pyridin-3-yl}acetic acid hydrochloride (CAS 1803608-72-1)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com