Esmolol Impurity 48 CAS CATO-C4X-189148
| CAS No. | CATO-C4X-189148 |
| Molecular Formula | C13H14O4 |
| Molecular Weight | 234.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Esmolol Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Esmolol Impurity 48 (CAS CATO-C4X-189148), a pharmacopoeial impurity reference standard (molecular formula C13H14O4, MW 234.25 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Esmolol Impurity 48 (C13H14O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H14O4 |
| Molecular Weight | 234.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Esmolol Standards
- Esmolol Impurity 87 (CAS CATO-C4X-189187)
- Esmolol Impurity N2 (CAS 112805-58-0)
- Esmolol Impurity 54 (CAS CATO-C4X-189154)
- Esmolol Impurity 67 (CAS CATO-C4X-189167)
- Esmolol Impurity 8 (CAS 81147-94-6)
- Esmolol Impurity 78 (CAS CATO-C4X-189178)
- Esmolol Impurity 21 (CAS CATO-C4X-189121)
- Esmolol Impurity 20 (CAS 2167848-51-1)
Recommended Standards
- Letrozole Impurity 6 (CAS 134521-16-7)
- Lusutrombopag Impurity 24 (CAS CATO-C4X-208424)
- Ertapenem Impurity Pro-maba (CAS 724700-26-9)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
- Avatrombopag Impurity 61 (CAS CATO-C4X-223461)
- CAS CATO-C3D-262787 (CAS CATO-C3D-262787)
- Fluticasone Impurity 87 (CAS CATO-C4X-165087)
- (R)-3-(fluoromethyl)-1-methylpiperazine (CAS 2387560-48-5)
- Edoxaban Impurity 117 (CAS 2230882-27-4)
- N-(2-(Cyclohex-1-en-1-yl)ethyl)-5-(N-cyclopropylsulfamoyl)furan-2-carboxamide (CAS 1147755-65-4)
- 2-(Benzyloxy)morpholine hydrochloride (CAS 89220-83-7)
- 4-Methylpiperidine-4-carbonitrile (CAS 948988-53-2)
- 5-Fluoro-2-nitro-4-(trifluoromethyl)aniline (CAS 428871-73-2)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com