Methylene blue /Methylthioninium Chloride Impurity 26 CAS CATO-C4X-189626
| CAS No. | CATO-C4X-189626 |
| Molecular Formula | C15H16N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Methylene blue /Methylthioninium Chloride Impurity 26 (C15H16N3SHO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Methylene blue /Methylthioninium Chloride Impurity 26 (CAS CATO-C4X-189626, C15H16N3SHO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Methylene blue /Methylthioninium Chloride Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H16N3S HO4S |
| Molecular Weight | 367.44 g/mol |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Methylene Standards
- γ-Methylene-γ-butyrolactone (CAS 10008-73-8)
- 4,4＇-Methylene-Bis(2-chloroaniline) (CAS 101-14-4)
- 5-Methylene-2-phenyl-1,3-dioxolan-4-one (CAS 101822-11-1)
- 2-Methylene-1,3,6-trioxocane (CAS 105649-50-1)
- 6-Methyl-3-methylene-3,4-dihydroquinoxalin-2(1H)-one (CAS 106480-88-0)
- 5-Methylene-2(5H)-furanone (CAS 108-28-1)
- 3-(2-Methylene-4-phenylbutanoyl)oxazol-2(3H)-one (CAS 1151767-07-5)
- (Methylene-d2)gibberellin A5 (CAS 120396-32-9)
Recommended Standards
- Ertapenem Impurity 57 (CAS CATO-C4X-163357)
- Morinidazole Impurity N3 (CAS 1807608-40-7)
- Telmisartan Impurity 53 (CAS 301533-59-5)
- 2-Bromoimidazo[5,1-b]thiazole (CAS 713107-45-0)
- 2-Amino-5-bromo-3-fluorobenzene-1-thiol (CAS 1020745-85-0)
- Quinacrine, Mepacrine (CAS 83-89-6)
- 3-Allylanisole (CAS 24743-14-4)
- Fluvoxamine impurity 139 (CAS CATO-C4X-195139)
- Bumetanide Impurity 15 (CAS CATO-C4X-198615)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com