Lenalidomide Impurity 65 HCl CAS CATO-C4X-190365
| CAS No. | CATO-C4X-190365 |
| Molecular Formula | C14H20Br2N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lenalidomide Impurity 65 HCl (C14H20Br2N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Lenalidomide Impurity 65 HCl (CAS CATO-C4X-190365), a pharmacopoeial impurity reference standard (molecular formula C14H20Br2N2OHCl, MW 428.59 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H20Br2N2O HCl |
| Molecular Weight | 428.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Lenalidomide Standards
- Lenalidomide Impurity 43 (CAS 1061604-41-8)
- Lenalidomide Impurity 51 (CAS 1063995-41-4)
- Lenalidomide Impurity 42 (CAS 1063995-49-2)
- Lenalidomide Impurity 37 (CAS 1063995-54-9)
- Lenalidomide Impurity 7 (CAS 1198299-53-4)
- Lenalidomide Impurity 37 (CAS 1198299-72-7)
- Lenalidomide Impurity 25 (CAS 1218910-61-2)
- rac-Lenalidomide-13C5 (CAS 1219332-91-8)
Recommended Standards
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Vortioxetine Impurity 148 (CAS CATO-C4X-1056148)
- Betamethasone Dipropionate EP Impurity F (CAS 66917-44-0)
- Vortioxetine impurity 158 (CAS CATO-C4X-1056158)
- 5-Bromo-4-(chloromethyl)-1-methyl-1H-pyrazole (CAS 1879308-39-0)
- 4-Hydroxythiomorpholine 1,1-dioxide (CAS 16043-39-3)
- Methyl 2-(2-(4-fluorophenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)acetate (CAS 477710-56-8)
- 5-bromo-4-methyl-1,3-dihydro-2-benzofuran-1-one (CAS 1255206-67-7)
- 3-Hydroxynaphthalene-1-sulfonic acid (CAS 6357-85-3)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com