Betamethasone Dipropionate EP Impurity F CAS 66917-44-0
| CAS No. | 66917-44-0 |
| Molecular Formula | C28H36O7 |
| Molecular Weight | 484.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Betamethasone Dipropionate EP Impurity F (C28H36O7) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Betamethasone Dipropionate EP Impurity F (CAS 66917-44-0) is a certified pharmaceutical impurity reference standard with the molecular formula C28H36O7 and a molecular weight of 484.58 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Betamethasone Dipropionate EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H36O7 |
| Molecular Weight | 484.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
Related Betamethasone Standards
- Betamethasone Impurity 139 (CAS CATO-C4X-1437139)
- Betamethasone Impurity 76 (CAS 5534-01-0)
- Betamethasone impurity 59 (CAS CATO-C4X-143759)
- Betamethasone Dipropionate EP Impurity D (CAS 5514-81-8)
- Betamethasone Impurity 21 (CAS 154713-07-2)
- Betamethasone Succinate (CAS 27297-42-3)
- Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) (CAS 1062-09-5)
- Betamethasone Impurity N82 (CAS 123013-29-6)
Recommended Standards
- Ivabradine Impurity 68 (CAS CATO-C4X-111968)
- Beclometasone Impurity 43 (CAS CATO-C4X-147443)
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- 9,10-Bis(6-phenylpyridin-3-yl)anthracene (CAS 1257879-34-7)
- Micafungin Impurity 8 (CAS CATO-C4X-16958)
- Acamprosate EP Impurity B Calcium Salt (Acamprosate USP Related Compound B) (CAS 3093141-49-9)
- Entecavir Impurity 51 (CAS CATO-C4X-107751)
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- 8-Methyl-3,4-dihydro-2h-1-benzopyran-4-amine hydrochloride (CAS 191608-12-5)
- 4-Ethoxy-2,6-difluoroaniline (CAS 1017779-79-1)
- N-methyl-2-(2-phenylacetyl)hydrazine-1-carbothioamide (CAS 51291-26-0)
- Eldecalcitol Impurity 36 (CAS 1101133-55-4)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com