Rotigotine Impurity 21 CAS CATO-C4X-192721
| CAS No. | CATO-C4X-192721 |
| Molecular Formula | C19H24BrNOS |
| Molecular Weight | 394.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Rotigotine Impurity 21 (CAS CATO-C4X-192721, C19H24BrNOS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rotigotine Impurity 21 (C19H24BrNOS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 394.37 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Rotigotine Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H24BrNOS |
| Molecular Weight | 394.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rotigotine Standards
- Rotigotine Sulfate (CAS 128478-69-3)
- Rotigotine EP Impurity G (CAS 1422357-33-2)
- Rotigotine Impurity 20 (CAS CATO-C4X-192720)
- Rotigotine Impurity 38 (CAS CATO-C4X-192738)
- Rotigotine Impurity 22 (CAS 1196459-54-7)
- Rotigotine Racemate HCl (CAS 102120-99-0)
- rac-Rotigotine-D3 Methyl Ether Amide (CAS 1246814-64-1)
- Rotigotine EP Impurity H (CAS 1148154-91-9)
Recommended Standards
- β-D-Glucopyranose, 4,6-O-(phenylmethylene)-, triacetate (CAS 60618-81-7)
- Fezolinetant Impurity 31 (CAS CATO-C4X-327031)
- N-(3-acetylphenyl)-2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carboxamide (CAS 957037-27-3)
- 1-Hydroxypyrene b-D-Glucuronide (CAS 154717-05-2)
- Mianserin Impurity 96 (CAS CATO-C4X-136996)
- Carbocisteine Impurity 26 (CAS CATO-C4X-201026)
- Famotidine EP Impurity J HCl (CAS 1798006-30-0)
- Methyl 3-sulfamoylbenzoate (CAS 59777-67-2)
- 1-(2-Bromoethyl)-1H-pyrazole-4-carboxylic acid (CAS 1403566-74-4)
- 2-methoxy-N-(2-methylpropyl)pyridin-4-amine (CAS 1550922-57-0)
- 3-(Bromomethyl)-4-methyl-4h-1,2,4-triazole hydrobromide (CAS 1417566-92-7)
- 4-((2-Oxopiperazin-1-yl)methyl)benzonitrile (CAS 406496-43-3)
- 3-Hydroxy-2-(quinazolin-4-ylamino)-butyric acid (CAS 1008675-44-2)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
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