Famotidine EP Impurity J HCl CAS 1798006-30-0
| CAS No. | 1798006-30-0 |
| Molecular Formula | C9H14N4O2S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Famotidine EP Impurity J HCl (CAS 1798006-30-0, C9H14N4O2S2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Famotidine EP Impurity J HCl (C9H14N4O2S2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 310.81 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14N4O2S2 HCl |
| Molecular Weight | 310.81 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Famotidine Standards
- Famotidine impurity HCl, >98% (CAS 100599-91-5)
- Famotidine EP Impurity I (CAS 1020719-36-1)
- Famotidine EP Impurity C (CAS 106433-44-7)
- Famotidine Impurity 23 (CAS 106649-95-0)
- Famotidine EP Impurity H (CAS 106649-96-1)
- Famotidine EP Impurity F (CAS 107880-74-0)
- Famotidine EP Impurity B Dimaleate (CAS 109467-08-5)
- Famotidine impurity 01 (CAS 1185040-73-6)
Recommended Standards
- Polmacoxib Impurity 5 (CAS 1778703-66-4)
- Nintedanib Impurity 186 (CAS CATO-C4X-1814186)
- Ursodeoxycholic Acid Impurity 109 (CAS CATO-C4X-1422109)
- 3-Bromo-N-(4-hydroxyphenyl)propanamide (CAS 929034-43-5)
- N-(3-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide (CAS 2121512-86-3)
- 1-(1-Ethyl-2,3-dihydro-1H-indol-5-yl)-ethanone (CAS 1600930-98-0)
- Methyl 2-methoxy-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 887408-51-7)
- 2-(Difluoromethoxy)-5-mercaptophenylpropanal (CAS 1805875-09-5)
- 3-([1,1-Biphenyl]-4-ylmethoxy)pyrrolidine (CAS 946726-60-9)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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