Tolvaptan Impurity 74 CAS CATO-C4X-195574
| CAS No. | CATO-C4X-195574 |
| Molecular Formula | C10H9Cl2NO |
| Molecular Weight | 230.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tolvaptan Impurity 74 (CAS CATO-C4X-195574, C10H9Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tolvaptan Impurity 74 (C10H9Cl2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolvaptan Impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9Cl2NO |
| Molecular Weight | 230.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tolvaptan Standards
- Tolvaptan Impurity 77 (CAS CATO-C4X-195577)
- Tolvaptan Impurity 107 (CAS 2735310-65-1)
- Tolvaptan Impurity 38 (CAS 3951-89-1)
- Tolvaptan Impurity 78 (CAS 1863916-82-8)
- Tolvaptan Impurity 106 (CAS 792931-77-2)
- Tolvaptan Impurity 37 (CAS 607-86-3)
- Tolvaptan Impurity 86 (CAS 108166-22-9)
- Tolvaptan Impurity N2 (CAS 30459-70-2)
Recommended Standards
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- Ceftazidime Impurity 107 (CAS CATO-C4X-1212107)
- Ketotifen Impurity 32 (CAS 81759-45-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com