Bumetanide Impurity 105 CAS CATO-C4X-1986105
| CAS No. | CATO-C4X-1986105 |
| Molecular Formula | C7H4N2O7 |
| Molecular Weight | 228.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carbohydrate-derived structure, an amide group, Bumetanide Impurity 105 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Bumetanide Impurity 105 (CAS CATO-C4X-1986105, C7H4N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bumetanide Impurity 105 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4N2O7 |
| Molecular Weight | 228.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Bumetanide Standards
- Bumetanide Impurity 75 (CAS CATO-C4X-198675)
- Bumetanide Impurity 41 (CAS 20532-06-3)
- Bumetanide Impurity 26 (CAS CATO-C4X-198626)
- Bumetanide Impurity 45 (CAS 860694-39-9)
- Bumetanide Impurity 95 (CAS 688318-18-5)
- Bumetanide Impurity 54 (CAS CATO-C4X-198654)
- Bumetanide Impurity 14 (CAS 118-97-8)
- Bumetanide Impurity 117 (CAS 74917-54-7)
Recommended Standards
- 66504-40-3 5W2YA6F455 DOV-216303 free base UNII-5W2YA6F455 DOV 216,303 free base (+/-)-Amitifadine 1-(3,4-Dichlorophenyl)-3-azabicyclo(3.1.0)hexane 3-Azabicyclo(3.1.0)hexane, 1-(3,4-dichlorophenyl)- 3-Azabicyclo(3.1.0)hexane, 1-(3,4-dichlorophenyl)-, (+/-)- (CAS 66504-40-3)
- 3,5-Dinitro-4-hydroxybenzoic acid (CAS 1019-52-9)
- 2-(2,3,4,5,6-Pentafluorophenoxy)ethanol 2-(2,3,4,5,6-pentafluorophenoxy)ethanol,90-93%,tech. 2-(2,3,4,5,6-pentafluorophenoxy)ethanol,93% 2-(Pentafluorophenoxy)ethanol 2-Pentafluorophenoxyethanol 2192-55-4 timtec-bb sbb006617 (CAS 2192-55-4)
- 3,5-Dinitrosalicylic Acid (CAS 609-99-4)
- Ticagrelor Impurity 141 (CAS CATO-C4X-1093141)
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