Bumetanide Impurity 75 CAS CATO-C4X-198675
| CAS No. | CATO-C4X-198675 |
| Molecular Formula | C14H13NO2 |
| Molecular Weight | 227.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Bumetanide Impurity 75 (CAS CATO-C4X-198675, C14H13NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bumetanide Impurity 75 (C14H13NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bumetanide Impurity 75 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13NO2 |
| Molecular Weight | 227.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 105 (CAS CATO-C4X-1986105)
- Bumetanide Impurity 41 (CAS 20532-06-3)
- Bumetanide Impurity 26 (CAS CATO-C4X-198626)
- Bumetanide Impurity 45 (CAS 860694-39-9)
- Bumetanide Impurity 95 (CAS 688318-18-5)
- Bumetanide Impurity 54 (CAS CATO-C4X-198654)
- Bumetanide Impurity 14 (CAS 118-97-8)
- Bumetanide Impurity 117 (CAS 74917-54-7)
Recommended Standards
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- Brivaracetam Impurity 78 (CAS CATO-C4X-200778)
- Alogliptin impurity 80 (CAS 2819242-71-0（free base）)
- Cefepime EP Impurity D Sodium Salt (CAS 78172-35-7)
- Olmesartan Impurity 65 (CAS 2101308-74-9)
- Diosmin Impurity 9 (CAS 3070516-52-5)
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- Ethacridine Impurity C53 (CAS 20304-70-5)
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- 2-(Tert-butyl)-3-formyl-1H-indole-5-carbonitrile (CAS 587828-18-0)
- Methyl 3-hydroxy-6-phenylpicolinate (CAS 144233-92-1)
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