Clenbuterol impurity 12 CAS CATO-C4X-199312

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-199312
Molecular FormulaC8H6BrCl2N
Molecular Weight266.95 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Clenbuterol impurity 12 CAS CATO-C4X-199312 chemical structure

Description

The occurrence of Clenbuterol impurity 12 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Clenbuterol impurity 12 (CAS CATO-C4X-199312), a pharmacopoeial impurity reference standard (molecular formula C8H6BrCl2N, MW 266.95 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Clenbuterol impurity 12 (C8H6BrCl2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 266.95 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H6BrCl2N
Molecular Weight266.95 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity>95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl/Br-containing
Nitrogen Atoms1

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