Fluconazole Impurity 8 CAS 163921-62-8
| CAS No. | 163921-62-8 |
| Molecular Formula | C13H10F2N6 |
| Molecular Weight | 288.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Fluconazole Impurity 8 (CAS 163921-62-8), a pharmacopoeial impurity reference standard (molecular formula C13H10F2N6, MW 288.26 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fluconazole Impurity 8 (C13H10F2N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fluconazole Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10F2N6 |
| Molecular Weight | 288.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Fluconazole Standards
- Fluconazole Impurity 10 (CAS 163921-61-7)
- Fluconazole EP Impurity D (CAS 81886-51-3)
- Fluconazole Impurity 19 (CAS 1348664-75-4)
- Fluconazole Impurity 26 (CAS CATO-C4X-101926)
- Fluconazole EP Impurity A (CAS 89429-59-4)
- Fluconazole EP Impurity A (R-Isomer) (CAS CATO-C4X-101963)
- Fluconazole (CAS 86386-73-4)
- Fluconazole Impurity 37 (CAS CATO-C4X-101937)
Recommended Standards
- Mesalazine EP Impurity S (CAS 1797983-23-3)
- 502651-46-9 7-Oxo-7-[4-(trifluoromethyl)phenyl]heptanoic acid DTXSID60620425 (CAS 502651-46-9)
- Nicardipine Impurity 24 (CAS 102993-38-4)
- Tert-butyl 3-oxo-3-(4-(trifluoromethyl)phenyl)propanoate (CAS 502424-53-5)
- Triclabendazole Impurity 5 (CAS 106791-37-1)
- Thioctic acid Impurity 43 (CAS 46236-19-5)
- Cholesterol Impurity 25 (CAS CATO-C4X-196725)
- 5-Ethyl-4-(1-tosylethyl)-1-(4-(trifluoromethoxy)phenyl)-1,3-dihydro-2H-imidazol-2-one (CAS 439096-02-3)
- Methyl 4-(pyrrolidin-2-yl)benzoate hydrochloride (CAS 1203685-30-6)
- 1-(Methylsulfonyl)-N-(4-(pyridin-2-yl)thiazol-2-yl)piperidine-4-carboxamide (CAS 1021265-73-5)
- 4-(dimethylamino)-4-phenylbutanoic acid hydrochloride (CAS 1820705-88-1)
- 6-Chloro-3,3-dimethyl-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione (CAS 1849591-66-7)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(5-methyl-3-(morpholine-4-carbonyl)-1H-pyrazol-1-yl)acetamide (CAS 1172868-15-3)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com