Crisaborole Impurity 25 CAS CATO-C4X-202125
| CAS No. | CATO-C4X-202125 |
| Molecular Formula | C13H8BrNO3 |
| Molecular Weight | 306.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Crisaborole Impurity 25 (CAS CATO-C4X-202125) is a certified pharmaceutical impurity reference standard with the molecular formula C13H8BrNO3 and a molecular weight of 306.11 g/mol.
Based on its molecular formula C13H8BrNO3, Crisaborole Impurity 25 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 306.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Crisaborole Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8BrNO3 |
| Molecular Weight | 306.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Crisaborole Standards
- Crisaborole Impurity 23 (CAS CATO-C4X-202123)
- Crisaborole Impurity 24 (CAS CATO-C4X-202124)
- Crisaborole Impurity 102 (CAS CATO-C4X-2021102)
- Crisaborole impurity 112 (CAS CATO-C4X-2021112)
- Crisaborole Impurity 135 (CAS CATO-C4X-2021135)
- Crisaborole impurity 153 (CAS CATO-C4X-2021153)
- Crisaborole impurity 154 (CAS CATO-C4X-2021154)
- Crisaborole Impurity 33 (CAS 906673-45-8)
Recommended Standards
- 1-(2-Fluoro-4-iodophenyl)piperazine (CAS 1121613-61-3)
- N-(4-Nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1150271-73-0)
- n-(1h-Benzo[d]imidazol-2-yl)-5-bromofuran-2-carboxamide (CAS 313231-24-2)
- 2-((4-Bromophenyl)amino)-1H-purin-6(9H)-one (CAS 123994-72-9)
- Risperidone Impurity 39 (CAS CATO-C4X-111139)
- Brinzolamide Impurity 21 (CAS CATO-C4X-194021)
- Bendamustine Impurity 39 (CAS CATO-C4X-127139)
- 2-(Piperidin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1283179-56-5)
- Abiraterone Impurity 12 (CAS CATO-C4X-107012)
- Methyl 3-(5-Chloro-2-hydroxyphenyl)-1H-pyrazole-5-carboxylate (CAS 187225-50-9)
- 2,6,9-Trimethylphenanthrene (CAS 66271-32-7)
- 1,8-Diiodoanthracene (CAS 189105-78-0)
- (Cyanomethyl)glycine (CAS 74784-64-8)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
Why CATO?
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